Bone Marrow Origin of Coronary Artery Diseases: The Impact of the Local Renin-Angiotensin System

The renin-angiotensin system (RAS) has both important systemic circulatory and local effects. The effects of local cardiac RAS on the cardiovascular system have been increasingly researched. In this study, we review the relationship between local bone marrow and local cardiac RAS and their impacts on atherosclerosis.