Abstract
BACKGROUND: P-wave duration and P-wave dispersion (PWD) give information about inhomogeneous and discontinuous atrial conduction, which are believed to be the leading electrophysiological causes of atrial fibrillation. The aim of this study was to investigate the effect of percutaneous chronic total occlusion (CTO) revascularization on P-wave duration and PWD in electrocardiography (ECG). MATERIALS AND METHODS: We enrolled 98 consecutive patients with sinus rhythm who underwent percutaneous coronary interventions (PCIs) for CTO. The maximum (Pmax) and minimum P-wave duration and PWD were measured before CTO interventions and at the first and sixth months after the procedure. RESULTS: There was no significant differences between the successful and failed CTO PCI groups in pre-procedural demographic, clinical, laboratory, angiographic data, and ECG parameters. Pmax values and PWD at 1 month and 6 months after successful CTO PCI were statistically lower than those at baseline (p < 0.001), while there was no significant change in the failed CTO PCI group. PWD values were significantly lower at 6 months of follow-up, regardless of the target vessel (p = 0.010, p < 0.001, p < 0.001; for left anterior descending, circumflex and right coronary artery, respectively). Compared to pre-CTO values in all Rentrop classes, PWD values were significantly lower at the sixth month. CONCLUSIONS: This study demonstrated that Pmax and PWD, which are risk factors for atrial arrhythmias, significantly reduced within 1 and 6 months after successful CTO PCI irrespective of the target vessel.