EPIDEMOLOGICAL, RADIOGRAPHIC AND PROGNOSTIC EVALUATION OF CHONDROBLASTOMA

软骨母细胞瘤的流行病学、放射学和预后评估

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Abstract

OBJECTIVE: To describe the clinical and imaging characteristics of chondroblastoma and identify possible factors related to joint complications. METHOD: This retrospective cohort study was carried out with data from the medical records of 23 patients diagnosed with chondroblastoma, subjecting them to statistical analyses. RESULT: In total, 19 patients were included, 12 (63.2%) of which were mean with a mean age of 13.6±3.5 year. The relation with the local dimension equaled 57.9%, higher in the apophysis of the greater trochanter: 95.2% (p<0.001). Based on imaging, 15.8% patients had an open physis; 55.6%, no damaged physeal line; 42.1%, cortical rupture; 21.1%, secondary aneurysmal bone cyst; 26.7%, violated cartilage; and all cases, medullary edema. 15.8% of cases showed local recurrence and no metastasis. Moreover, 46.7% of patients had relevant secondary osteoarthritis related to the aggressiveness of the tumor according to the Enneking classification (p= 0.041). CONCLUSION: The clinical outcome of chondroblastoma show no relation to age, sex, location, physeal status, or presence of calcifications or secondary aneurysmal bone cyst. Progression to secondary osteoarthritis configured the most frequent non-oncological complication and showed a direct relation with the severity of the chondroblastoma. Level of Evidence IV, Case Series.

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