Aims
Berberine (BBR) is one of isoquinoline alkaloids from Coptidis Rhizoma and possesses extensive pharmacological activities, including anti-colorectal cancer (CRC) activity. However, the detailed mechanisms remain to be determined. The current study aims to investigate the ability and the potential mechanism of BBR against CRC. Main
Methods
By mining recognized CRC datasets and RNA-seq
Significance
Our data might provide a theoretical basis for the future use of BBR in colorectal cancer prevention.