Abstract
This issue of the Journal focuses on issues in the intersection of nutritional science and cancer prevention research. In this commentary, we provide a high-level orientation for the reader to nutrition and cancer. We begin by reviewing the burden of cancer which has necessitated public policy recommending improvements to diet for the prevention of cancer in the U.S., although this is true of many other countries as well. These policy recommendations are based on the critical review of scientific evidence linking diet and cancer. We then discuss the inconsistencies in the nutrition-cancer scientific literature and the subsequent issues Registered Dietitian Nutritionists (RDNs) face when translating this literature in the clinic. We conclude with some resources for practitioners and general guidance.