Occurrence of Extended-Spectrum and AmpC-Type β-Lactamase Genes in Escherichia coli Isolated from Water Environments in Northern Thailand

泰国北部水环境中分离的大肠杆菌中超广谱和AmpC型β-内酰胺酶基因的出现

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Abstract

Sixty-eight cefotaxime-resistant Escherichia coli isolates were recovered from different water environments in Northern Thailand. Isolates were mostly resistant to ceftazidime and aztreonam (>90%). The most common extended-spectrum β-lactamase-encoding gene was bla(CTX-M-group 1) (75%) followed by bla(CTX-M-group 9) (13.2%). The co-existence of bla(CTX-M) and AmpC-type β-lactamase genes was detected in 4 isolates (5.9%). Two E. coli isolates carrying bla(CTX-M) from canal and river water samples belonged to the phylogenetic group B2-ST131, which is known to be pathogenic. This is the first study on bla(CTX-M) and bla(CMY-2)-carrying E. coli and the emergence of ST131 from water environments in Thailand.

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