Are intraspinal anomalies in early onset idiopathic scoliosis as common as once thought? A two centre United Kingdom study

早发性特发性脊柱侧弯患者的椎管内异常是否像之前认为的那样常见?一项英国两中心的研究

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Abstract

PURPOSE: Rates of neural axis abnormalities in infantile and juvenile idiopathic scoliosis may be as high as 50 %. We aimed to determine the rates of neural axis abnormalities in early onset idiopathic scoliosis patients in a British population. METHODS: This retrospective study at two British spinal deformity clinics identified 72 patients satisfying the inclusion criteria of: (1) age at diagnosis of 7 years and younger, (2) idiopathic scoliosis and (3) magnetic resonance imaging of the neuraxis. RESULTS: The mean age at diagnosis was 3.6 years and the mean Cobb angle was 47° with a near equal distribution of left (32) and right (36) sided curves. Eight (11.1 %) neural axis abnormalities consisting of two syrinxes, one Arnold-chiari Type I malformation and five combined (Arnold-chiari malformation Type I and syrinx) anomalies were identified. CONCLUSIONS: This multi-centre study on the largest number of British subjects to date helps to establish the rates of neural axis abnormalities.

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