Abstract
BACKGROUND: Content generated by artificial intelligence is sometimes not truthful. To date, there have been a number of medical studies related to the validity of ChatGPT's responses; however, there is a lack of studies addressing various aspects of statistical analysis. The aim of this study was to assess the validity of the answers provided by ChatGPT in relation to statistical analysis, as well as to identify recommendations to be implemented in the future in connection with the results obtained. METHODS: The study was divided into four parts and was based on the exemplary medical field of allergology. The first part consisted of asking ChatGPT 30 different questions related to statistical analysis. The next five questions included a request for ChatGPT to perform the relevant statistical analyses, and another five requested ChatGPT to indicate which statistical test should be applied to articles accepted for publication in Allergy. The final part of the survey involved asking ChatGPT the same statistical question three times. RESULTS: Out of the 40 general questions asked that related to broad statistical analysis, ChatGPT did not fully answer half of them. Assumptions necessary for the application of specific statistical tests were not included. ChatGPT also gave completely divergent answers to one question about which test should be used. CONCLUSION: The answers provided by ChatGPT to various statistical questions may give rise to the use of inappropriate statistical tests and, consequently, the subsequent misinterpretation of the research results obtained. Questions asked in this regard need to be framed more precisely.