Bladder wall thickness and detrusor wall thickness can help to predict the bladder outlet obstruction in men over the age of 70 years with symptomatic benign prostatic hyperplasia

膀胱壁厚度和逼尿肌壁厚度可以帮助预测70岁以上有症状良性前列腺增生男性的膀胱出口梗阻。

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Abstract

PURPOSE: We investigated the possible association between preoperative bladder wall thickness (BWT) or detrusor wall thickness (DWT) and bladder outlet obstruction (BOO) based on urodynamic studies in men with symptomatic benign prostatic hyperplasia (BPH). MATERIALS AND METHODS: Data were prospectively collected from a BPH surgery database. A total of 196 men who underwent prostate vaporization for symptomatic BPH were included in this study. BWT and DWT were measured in the suprapubic area after uroflowmetry. RESULTS: No significant difference was noted in BWT and DWT in any patient according to the presence of BOO; however, subgroup analysis showed that BWT and DWT were significantly thicker in the obstruction group in men aged 70 years or older than in those under age 70 (BWT: 3.6+0.9 mm vs. 3.1+0.9 mm, p=0.022, DWT: 2.8±0.8 mm vs. 2.3±0.8 mm, p=0.007). In this older age group, the classification based on a BWT ≥4.0 mm showed 31% sensitivity, 87% specificity, and 65% diagnostic accuracy for the diagnosis of BOO, whereas DWT ≥3.0 mm showed 49% sensitivity, 82% specificity, and 69% diagnostic accuracy. CONCLUSIONS: BWT and DWT were associated with BOO in men aged 70 years or older. Therefore, BWT and DWT will be a useful non-invasive parameter for deciding the management strategy for elderly men with symptomatic BPH. An appropriate measurement method should be established as soon as possible for further application of the relationship among BWT, DWT and BOO.

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