Abstract
This study examines how proteinoids and myelin interact in biomimetic neural systems. These interactions reveal electrochemical properties and computing capabilities. Proteinoids are made when amino acids heat up and bond together. They form microspheres that can produce electrical signals on their own. Myelin, on the other hand, acts as an insulator and conductor, which is essential for nerve signaling. We studied proteinoid-myelin hybrid systems. We used scanning electron microscopy, electrochemical impedance spectroscopy, and recorded extracellular potential for over 180,000 s. The hybrid structures show complex electrical behaviors. These include spontaneous spike generation, phase transitions, and oscillatory patterns. The membrane potentials range from -90 mV to +70 mV. Equivalent circuit analysis showed that hybrid systems had higher capacitance (159.3 nF) and lower impedance (3.934 kΩ) than pure proteinoid microspheres. We used threshold-based signal processing to perform full Boolean logic operations. This was done by tapping into the bioelectrical activity of these hybrid systems. This research shows that simple biomolecular parts can come together to form structures. These structures can perform complex computations. This finding hints at uses in biocompatible computing, neuromorphic engineering, and bioelectronic interfaces.