Abstract
OBJECTIVES: Because they are potentially modifiable and may coexist, we evaluated the combined occurrence of a reduced forced expiratory volume in 1 second (FEV1) and peripheral artery disease (PAD), including its association with exertional symptoms, physical inactivity, and impaired mobility, in sedentary elders with functional limitations. DESIGN: Cross sectional. SETTING: Lifestyle Interventions and Independence in Elder (LIFE) Study. PARTICIPANTS: A total of 1307 sedentary community-dwelling persons, mean age 78.9, with functional limitations (Short Physical Performance Battery [SPPB] <10). MEASUREMENTS: A reduced FEV1 was defined by a z-score less than -1.64 (