Abstract
WHAT IS ALREADY KNOWN ABOUT THIS TOPIC? Female breast nodules represent the most frequently detected lesions during breast ultrasound screening. Notably, nodules classified as Breast Imaging Reporting and Data System (BI-RADS) 4 or 5 indicate an elevated risk of breast cancer. Nevertheless, the detection rate and BI-RADS classification of female breast nodules in China remain largely undocumented. WHAT IS ADDED BY THIS REPORT? In 2021, breast nodules were detected in 27.9% of urban women in China. Among women with breast nodules marked with BI-RADS classification information, 95.9% were categorized as BI-RADS 2-3, while 4.0% were classified as BI-RADS 4-5. Age, geographic location, per capita gross domestic product (GDP), body mass index (BMI), high triglyceride (TG), high low-density lipoprotein cholesterol (LDL-C), and diabetes were identified as risk factors for BI-RADS 4-5. WHAT ARE THE IMPLICATIONS FOR PUBLIC HEALTH PRACTICE? This study highlights the importance of managing high-risk women with breast nodules through BI-RADS classification. Women with older age, high TG, high LDL-C, or diabetes demonstrate higher detection rates of BI-RADS 4-5, underscoring the need for targeted health interventions for high-risk populations while accounting for regional and socioeconomic disparities.