Abstract
WHAT IS ALREADY KNOWN ABOUT THIS TOPIC? Dimethylacetamide (DMA), a colorless liquid with low toxicity, is commonly used as a solvent in the production of synthetic materials, petroleum processing, and pharmaceutical manufacture. In comparison to substances of higher toxicity, occupational exposure to DMA presents a deceptive risk due to its insidious and subacute progression, increasing the likelihood of escalating into major incidents. WHAT IS ADDED BY THIS REPORT? In August 2023, an incident of occupational DMA poisoning involving six cases was reported at a spandex manufacturing factory in Zhuhai City, Guangdong Province, China, following post-fire management activities. All affected individuals were employees of an equipment maintenance company tasked with cleaning polymerizers. With the coordinated efforts of the health institutions in Guangdong Health Emergency Response Network for Poisoning Emergencies (HERNPE), the situation was promptly identified and addressed. WHAT ARE THE IMPLICATIONS FOR PUBLIC HEALTH PRACTICE? HERNPE serves as an effective framework for enhancing the integration of health institutions across various levels, facilitating a coordinated response that combines clinical services with public health initiatives. By leveraging the leadership of national centers, HERNPE plays a crucial role in the early detection, prevention, and management of large-scale health events.