Abstract
WHAT IS ALREADY KNOWN ABOUT THIS TOPIC? There is mounting evidence indicating that the aging process initiates during early life stages, with in utero the individual's environment playing a significant role. Consequently, it is crucial to comprehend the enduring effects of early life circumstances on health in old age. WHAT IS ADDED BY THIS REPORT? In this study, we conducted a meta-analysis to examine the effects of the Chinese Famine (1959-1961) on the health of older adults. We also explored potential mechanisms underlying these effects. WHAT ARE THE IMPLICATIONS FOR PUBLIC HEALTH PRACTICE? The complex interplay between early life circumstances, multiple health-related sectors, and healthy aging necessitates a comprehensive life-course approach and strategic interventions to enhance public health in an aging society.