Prevalence of High-Risk Human Papillomavirus in Cervical Intraepithelial Neoplasia in the Pre-Vaccine Era - China, 2017-2018

疫苗接种时代前中国宫颈上皮内瘤变中高危型人乳头瘤病毒的流行情况(2017-2018年)

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Abstract

WHAT IS ALREADY KNOWN ABOUT THIS TOPIC? Human papillomavirus (HPV) type-specific strategies play a key role in the prevention of cervical intraepithelial neoplasia (CIN), but evidence on the HPV type-specific prevalence in CIN is limited. WHAT IS ADDED BY THIS REPORT? This multicentric study estimates the prevalence of high-risk HPV types in CIN cases and the associations of HPV infection patterns with high-grade CIN in China in 2017-2018. WHAT ARE THE IMPLICATIONS FOR PUBLIC HEALTH PRACTICE? Population-based prevention strategies should give preference to HPV-16 and 18, and strategies for non-16/18 high-risk HPV are essential for the elimination of cervical cancer.

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