Therapeutic outcomes and analysis of Doppler findings in 25 patients with non-ischemic priapism

25例非缺血性阴茎异常勃起患者的治疗结果及多普勒超声检查结果分析

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Abstract

Non-ischemic priapism (NiP) is painless partial tumescence caused by genital trauma and the formation of intracorporal arterio-venous fistula. This is a retrospective study of 25 men with NiP and reports the long-term erectile function and colour doppler ultrasound (CDUS) findings after treatment for NiP. Unstimulated CDUS was performed at diagnosis, 1 week and at last follow-up after treatment. CDUS traces were analysed: peak systolic velocity (PSV), end diastolic velocity (EDV), resistive index (RI) and mean velocity (MV) were calculated. Erectile function was assessed using the IIEF-EF questionnaire. At the last follow-up (median 24 months), 16 men had normal erectile function (64%): median IIEF-EF score 29 (IQR 28.5-30; σ(2) 2.78) and nine had erectile dysfunction (36%): median IIEF-EF score 17 (IQR 14-22; σ(2) 33.6). MV and EDV were statistically higher in those patients with erectile dysfunction at last follow-up compared to patients with normal erectile function: median MV 5.3 cm/s (IQR 2.4-10.5 cm/s; σ(2) 34) vs 2.95 cm/s (IQR 1.03-3.95; σ(2) 3.4) p < 0.002 and median EDV 4.0 cm/s (IQR 1.5-8.0; σ(2) 14.7) vs 0 cm/s (IQR 0-1.75; σ(2) 2.21) p < 0.004. Erectile dysfunction was observed in 36% of men treated for NiP and was associated with abnormal low resistance resting CDUS waveforms. Further investigation for persistent arteriovenous fistulation should be considered in these patients.

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