Longitudinal quality of life assessment following robotic mitral valve repair versus conventional sternotomy

机器人辅助二尖瓣修复术与传统胸骨切开术后生活质量的纵向评估

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Abstract

OBJECTIVE: Robotic-assisted mitral repair has demonstrated excellent late outcomes without increased morbidity and mortality in experienced centers. Robust analysis of postoperative quality of life in large cohorts has been limited. METHODS: Between January 1, 2020, and April 1, 2024, 563 adult patients who underwent mitral repair for degenerative mitral regurgitation at our institution were retrospectively reviewed. Patient-Reported Outcomes Information System Global Health 10-question survey (PROMIS-10) physical and mental scores, as well as MacNew social scores were evaluated at baseline and serial follow-up at 1 month, 3 months, 6 months, and 1 year. Quality of life (QoL) metrics were evaluated longitudinally using a nonlinear multiphase mixed-effects regression model. RESULTS: A total of 1493 postoperative QoL measurements were available in 563 patients (247 robotic vs 316 sternotomy). Patients who received a robotic approach were younger than those who underwent sternotomy (age 58 ± 10 years vs age 66 ± 10 years; P < .001) with fewer comorbidities and higher baseline PROMIS-10 physical (55 robotic vs 51 sternotomy; P < .001) and mental (57 vs 53; P < .001) scores. There was no significant difference in temporal outcomes between groups (physical: P = .11; mental: P = .84; social: P = .55). Each metric in both groups surpassed the population norm and returned to preoperative baseline within 6 months (graphical abstract). CONCLUSIONS: Postoperative QoL following mitral valve repair was excellent, regardless of approach. Patients who were selected for a robotic approach demonstrated higher baseline QoL metrics than those who received a sternotomy, but this did not translate to a comparative improvement on adjusted analyses and QoL for most patients returned to baseline by 6 months. The operative approach for mitral valve repair in patients who are candidates for a minimally invasive procedure should be tailored to surgeon experience in offering a safe, durable repair.

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