Indirect Effects of PM(2.5) Exposure on COVID-19 Mortality in Greater Jakarta, Indonesia: An Ecological Study

PM2.5暴露对印度尼西亚大雅加达地区COVID-19死亡率的间接影响:一项生态学研究

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Abstract

BACKGROUND: Air pollution, including PM(2.5), was suggested as one of the primary contributors to COVID-19 fatalities worldwide. Jakarta, the capital city of Indonesia, was recognized as one of the ten most polluted cities globally. Additionally, the incidence of COVID-19 in Jakarta surpasses that of all other provinces in Indonesia. However, no study has investigated the correlation between PM(2.5) concentration and COVID-19 fatality in Jakarta. OBJECTIVE: To investigate the correlation between short-term and long-term exposure to PM(2.5) and COVID-19 mortality in Greater Jakarta area. METHODS: An ecological time-trend study was implemented. The data of PM(2.5) ambient concentration obtained from Nafas Indonesia and the National Institute for Aeronautics and Space (LAPAN)/National Research and Innovation Agency (BRIN). The daily COVID-19 death data obtained from the City's Health Office. FINDINGS: Our study unveiled an intriguing pattern: while short-term exposure to PM(2.5) showed a negative correlation with COVID-19 mortality, suggesting it might not be the sole factor in causing fatalities, long-term exposure demonstrated a positive correlation. This suggests that COVID-19 mortality is more strongly influenced by prolonged PM(2.5) exposure rather than short-term exposure alone. Specifically, our regression analysis estimate that a 50 µg/m3 increase in long-term average PM(2.5) could lead to an 11.9% rise in the COVID-19 mortality rate. CONCLUSION: Our research, conducted in one of the most polluted areas worldwide, offers compelling evidence regarding the influence of PM(2.5) exposure on COVID-19 mortality rates. It emphasizes the importance of recognizing air pollution as a critical risk factor for the severity of viral respiratory infections.

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