Efficacy of Amflow®, a Real-Time-Portable Feedback Device for Delivering Appropriate Ventilation in Critically Ill Patients: A Randomised, Controlled, Cross-Over Simulation Study

Amflow®(一种用于危重患者提供适当通气的实时便携式反馈装置)的疗效:一项随机、对照、交叉模拟研究

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Abstract

OBJECTIVE: The aim of this study was to test whether Amflow® (a newly designed portable ventilation feedback device) can assist rescuers in delivering target tidal volume (V (T)) and respiration rate (RR) during self-inflating bag (SB) ventilations in various clinical scenarios. METHOD: This was a simulation study with a prospective cross-over design. A total of 40 trained participants who underwent training for SB ventilation were recruited. Using a SB with or without Amflow® alternately, participants delivered ventilations to test lungs connected to a gas flow analyser in each of three different scenarios: acute respiratory distress syndrome (ARDS; 315-385 ml ranges for 350 ml target V (T), with 20 breaths/min); cardiopulmonary resuscitation (CPR; 450-550 ml ranges for 500 ml target V (T) with 10 breaths/min); and adult head trauma (630-770 ml ranges for 700 ml target V (T) with 15 breaths/min). RESULTS: The feedback group (SB with Amflow®) demonstrated a significantly higher percentage of delivering the appropriate V (T) ranges than the no-feedback group for both ARDS (58.6% versus 23.5%, respectively) and CPR (85.4% versus 41.0%, respectively) (all p < 0.05). However, there was no significant difference between the two groups in the percentage of delivering the appropriate V (T) ranges in head trauma patients (65.9% versus 68.3%, respectively; p=0.092). In all three scenarios, a higher percentage of target RR delivered was achieved in the feedback group (88.3%, 99.2%, and 96.3%, respectively) compared with the no-feedback group (5.8%, 12.5%, and 10.0%, respectively) (all p < 0.05). CONCLUSION: The Amflow® device could be useful for rescuers in delivering SB ventilation with appropriate V (T) and RR simultaneously in various critical situations, except for clinical cases that demand greater delivered V (T).

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