Spectrophotometric estimation of olmesartan medoxomil and hydrochlorothiazide in tablet

分光光度法测定片剂中奥美沙坦酯和氢氯噻嗪的含量

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Abstract

A simultaneous determination of olmesartan medoxomil and hydrochlorothiazide by absorption ratio spectrophotometric method has been developed in combined tablet dosage form. The method is based on measurements of absorbance at isoabsoptive point. The Beer's law obeys in the range of 10-30 mug/ml for both olmesartan medoxomil and hydrochlorothiazide respectively. The proposed method was validated by performing recovery study and statistically.

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