Determination of Artemisinin in Bulk and Pharmaceutical Dosage Forms using HPTLC

采用高效薄层色谱法测定原料药和药物制剂中青蒿素的含量。

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Abstract

A new, simple, rapid, accurate and precise HPTLC method was developed. The detector response was linear for concentrations between 100-600 ng/spot (r =0.9931). The limits of detection and quantitation were 25 ng/spot and 75 ng/spot, respectively. The recovery study was carried out by standard addition method and was found to be 99.60+/-0.27. Statistical analysis proved that the method was precise, accurate and reproducible, and hence was suitable for the routine analysis of artemisinin.

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