Microwave-induced synthesis of schiff bases of aminothiazolyl bromocoumarins as antibacterials

微波诱导合成氨基噻唑基溴香豆素席夫碱作为抗菌剂

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Abstract

A fast and highly efficient method for the synthesis of some of the schiff bases of aminothiazolylbromocoumarin (4a-m) has been performed by microwave irradiation of 2'-amino-4'-(6-bromo-3-coumarinyl) thiazole (3) and substituted aromatic aldehydes (a-m). Microwave assisted reactions have resulted in better yields of the desired products than when prepared under conventional conditions. The resulting products were evaluated for their qualitative and quantitative antibacterial activity.

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