The Evaluation of the Clinical Effects of Botulinum Toxin on Nocturnal Bruxism

肉毒杆菌毒素治疗夜间磨牙症的临床疗效评价

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Abstract

OBJECTIVES: Nocturnal bruxism can be managed by botulinum toxin (Botox®) in patients who have not responded to conservative treatment. The aim of this study was to evaluate the efficacy of botulinum toxin A (BTXA) in the treatment of nocturnal bruxism. MATERIAL AND METHODS: The retrospective study comprised 25 female patients, aged 23-55 years (mean 35.84 ± 8.41 years). All patients received a single injection of BTXA in the right and left masseters. Evaluation was made by Visual Analogue Scale (VAS) values, complaint duration, onset of effect, and duration of effectiveness. RESULTS: BTXA produced significant improvements in pain scores. Only 2 adverse events (8%) were recorded. CONCLUSION: BTX-A is effective in the treatment of nocturnal bruxism.

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