Important mitochondrial proteins in human omental adipose tissue show reduced expression in obesity
人类网膜脂肪组织中的重要线粒体蛋白在肥胖中表达减少
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作者:Peter W Lindinger, Martine Christe, Alex N Eberle, Beatrice Kern, Ralph Peterli, Thomas Peters, Kamburapola J I Jayawardene, Ian M Fearnley, John E Walker
| 期刊: | Journal of Proteomics | 影响因子: | 2.800 |
| 时间: | 2015 | 起止号: | 2015 Jun 21:124:79-87. |
| doi: | 10.1016/j.jprot.2015.03.037 | 种属: | Human |
| 研究方向: | 信号转导 | |
Significance
The finding that obese human subjects have reduced levels of important mitochondrial proteins in adipocytes of omental adipose tissue as compared to non-obese controls gives new insights in the impairment of mitochondrial function in this specialized compartment of human adipose tissue in obesity and may eventually lead to the definition of valuable obesity markers.
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