Abstract
Situs inversus totalis (SIT) is a rare condition with a genetic predisposition, wherein organs or organ systems are transposed from their normal sites to locations on the opposite side of the body (the mirror image of normal). The syndrome may include transposition of the thoracic viscera, the abdominal viscera, or more commonly, both. The incidence has been calculated variously as 1 in 6,000-35,000 live births. We present the case of a 22-year-old man with SIT with acute appendicitis. Patient was treated with laparoscopic appendicectomy which is invaluable in both diagnosis and treatment of such patients.