Abstract
A 48-year-old man with HIV infection (CD4 count = 84 cells/μL) experienced hematemesis and hematochezia. Colonoscopy revealed massive bleeding in the colon, in which the source of the bleeding could not be identified. A total colectomy was performed. A large superficial ulcer at the rectosigmoid colon was observed. Histologically, abundant cytomegalovirus (CMV)-infected cells were noted. The pathological diagnosis was CMV colitis.