Diffuse skin hyperpigmentation associated with chronic minocycline use in a patient with prosthetic joint infection

一名患有假体关节感染的患者,因长期使用米诺环素而出现弥漫性皮肤色素沉着过度。

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Abstract

Cutaneous hyperpigmentation is a recognized adverse effect of chronic minocycline use occurring in up to 50% of patients. In this report we present a rare case of extensive skin hyperpigmentation involving both lower extremities in a patient receiving long term minocycline. The patient was receiving minocycline as suppression for chronic prosthetic joint infection. Risk factors associated with minocycline-induced cutaneous pigmentation (MICH) will be reviewed.

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