Abstract
Opportunistic infection by Cryptococcus is one of the most common occurrences in patients with Human Immunodeficiency Virus (HIV) disease or Acquired Immunodeficiency Syndrome (AIDS); however, it is a very rare discovery in the immunocompetent. This encapsulated, aerobic fungus can be found in bird droppings, the soil, or on trees, and breathing the spores can lead to pneumonia, meningitis, sepsis, skin lesions, or disseminate throughout the body. We discuss the unique presentation of an immunocompetent former inmate who was admitted to the hospital due to symptoms of dyspnea and fever. After a thorough history, physical exam, and diagnostic testing, the patient was diagnosed with disseminated cryptococcosis. The patient has since made a complete recovery and was discharged home after receiving careful medical management.