A case of multiple abscesses caused by Nocardia farcinica rapidly diagnosed by MALDI-TOF MS

利用基质辅助激光解吸电离飞行时间质谱法(MALDI-TOF MS)快速诊断由法氏诺卡氏菌(Nocardia farcinica)引起的多发性脓肿病例

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Abstract

Identifying Nocardia species in routine tests is often difficult owing to its culture time. We report a case of nocardiosis characterized by multiple abscesses of disseminated disease. A man in his 50 's presented with inflammation on the left buttock and right lower leg. Nocardia farcinica was isolated from the abscess on his buttock and confirmed using matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS). Radiological assessment revealed multiple abscesses in his brain, left lung, and right thigh. He was successfully treated with antibiotics. Accurate species identification by MALDI-TOF MS aids in the optimal treatment of nocardiosis.

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