Abstract
Rhino-orbital-cerebral mucormycosis (ROCM) is an invasive mycosis caused by fungi of the order Mucorales. It mainly affects patients with uncontrolled diabetes. This case report concerns a 27-year-old woman with diabetic ketoacidosis who presented with a large erythematous plaque localised in the right orbitofrontal region with exophthalmos and patches of necrosis that rapidly led to death within 3 days before the diagnosis of ROCM due to Rhizopus oryzae, the causal agent. So, without rapid diagnosis and swift management, ROCM results in a potential fatality.