Fatal Pasteurella multocida pneumonia and bacteremia in a patient with chronic obstructive pulmonary disease: A case report with autopsy findings

慢性阻塞性肺疾病患者发生致命性多杀性巴氏杆菌肺炎和菌血症:病例报告及尸检结果

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Abstract

Pasteurella multocida (P. multocida) is a well-recognized pathogen responsible for skin and soft tissue infections following animal bites or scratches. Notably, it can also cause severe systemic infections in the absence of direct trauma, particularly in immunocompromised individuals. Herein, we report the case of a 75-year-old man with chronic obstructive pulmonary disease who presented with fever and rapidly progressive respiratory failure. Based on clinical, radiological, and microbiological findings, he was diagnosed with P. multocida pneumonia and bacteremia. Despite appropriate antibiotic therapy, the patient died 32 h after admission. Autopsy revealed diffuse bronchopneumonia and multiorgan dysfunction secondary to septic shock. This case highlights the importance of considering P. multocida infection in patients with underlying comorbidities and potential animal exposure, even in the absence of direct trauma.

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