Sphingomonas paucimobilis native valve endocarditis and mycotic cerebral aneurysm in a patient with Crohn's disease: Case report and review of literature

克罗恩病患者并发少动鞘氨醇单胞菌性原生瓣膜心内膜炎和真菌性脑动脉瘤:病例报告及文献复习

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Abstract

This report describes a case of Sphingomonas paucimobilis bacteremia and infective endocarditis with a mycotic aneurysm in a young patient with Crohn's disease. Our patient reported prolonged intermittent fever followed by sudden hemiparesis and a tonic clonic convulsion. His blood cultures showed growth of Sphingomonas paucimobilis, and further cardiac imaging revealed the presence of a vegetation with severe valvular regurgitation. Cerebral angiography showed middle cerebral artery occlusion and aneurysm. The patient was treated with meropenem for 6 weeks, coupled with aortic valve replacement, and coiling of the aneurysm. Our patient recovered with good results. S. paucimobilis is an opportunistic gram-negative pathogen of growing importance in the clinical setting.

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