A new multi-gram synthetic route to labeling precursors for the D(2/3) PET agent 18F-fallypride

一种新的多克级合成路线,用于标记D(2/3) PET显像剂18F-fallypride的前体。

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Abstract

This Letter describes a new multi-gram synthetic protocol for the preparation of the classic tosylate labeling precursor for the D(2/3) PET agent [(18)F]fallypride. In the course of our studies, we also discovered two novel labeling precusors, the previously undescribed mesylate and chloro congeners of fallypride.

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