Abstract
AIM: To evaluate the efficacy of spontaneous urination stimulation techniques in infants under 1 year to obtain a clean and valid urine sample for analysis. METHODS: Systematic review of randomised clinical trials. The databases consulted were PUBMED, SCOPUS, WEB OF SCIENCE, CINALH and the Virtual Health Library. The risk of bias was assessed via the RoB2 scale. A meta-analysis was performed to analyse the success rate of urine collection for both techniques and the contamination rate of the urine samples. RESULTS: Seven studies were included in this review. The participants included 1122 infants, of whom a stimulation technique was performed in 667 (the technique of Herreros et al. was performed in 419 infants, and the "Quick-Wee" technique was performed in 248 infants). Success was measured by obtaining a midstream urine sample in less than 5 min. Urination stimulation is effective in obtaining a urine sample, especially at < 6 months of age. CONCLUSION: Stimulation of urination in infants is a noninvasive, fast, safe, economic and effective procedure that allows the capture of a valid urine sample in the middle of the stream for analysis.