fac-Re(2,2'-bipyridine)(CO)(3)Cl Catalyzes Visible-Light-Driven Functionalization of an Organic Substrate with CO(2)

fac-Re(2,2'-联吡啶)(CO)3)Cl 催化可见光驱动的有机底物与 CO(2) 的功能化

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Abstract

The molecular photocatalyst fac-Re-(2,2'-bipyridine)-(CO)(3)Cl ([Re-Cl]) is well established and has been extensively investigated for the highly active and selective conversion of CO(2) to CO. However, its reactivity in processes other than CO(2) reduction has rarely been explored. Herein, we report the application of [Re-Cl] as a catalyst for the visible-light-driven carboxylation of an alkene using CO(2), with phenyl vinyl sulfone (1) serving as a model substrate. The catalytic system successfully catalyzed the carboxylation of 1 to its corresponding carboxylic acid, with complete suppression of CO formation throughout the reaction. A turnover number (TON) of up to 2600, along with excellent regioselectivity, was achieved under optimized conditions. Control experiments revealed the key role of each reaction component, while isotope labeling with (13)CO(2) confirmed that the carboxyl group originated from CO(2). Furthermore, mechanistic investigations suggested that the Re-CO(2) intermediate reacts directly with the alkene. These findings highlight the potential of Re-based molecular complexes for broader reactivities and expand their applicability in sustainable synthetic transformations.

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