Generation and Nitric Oxide Reactivity of a Cobalt(II) Superoxide Complex via Guanidine-Based Ligand Non-Innocence

通过胍基配体非无辜性生成钴(II)超氧化物络合物及其与一氧化氮的反应性

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Abstract

A novel guanidine-based NNN pincer cobalt-(II) complex, Co1, was investigated for dioxygen (O(2)) activation. Upon reaction with O(2) at room temperature, a μ-hydroxo-bridged Co(II)-OH-Co(II) complex (Co2) was isolated as the final oxygenated product. In-depth spectroscopic investigation revealed that the formation of Co2 occurs via an intermediate superoxide species (Co1-O (2) (•-) ), by taking advantage of the redox non-innocence behavior of the ligand (3,3'-(pyridine-2,6-diyl)-bis-(1-methyl-N-phenylimidazolidin-2-imine)), and therefore keeping the cobalt oxidation state unchanged at +2. Interestingly, the zinc analogue, Zn1, was also shown to yield a similar μ-hydroxo-bridged Zn(II)-OH-Zn(II) complex (Zn2) as the final product under the same aerobic conditions, providing further confirmation of the ligand influence on metal oxidation and spin states during O(2) activation. Further reactivity studies demonstrated that Co1-O (2) (•-) reacts with nitric oxide ((•)NO) to form a Co(II)-peroxynitrite (Co1-O NO(2) (-) ) intermediate, which performs an unprecedented intramolecular nitration of the phenyl moieties of the ligand at the para position.

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