Pd-Catalyzed Cross-Coupling of Alkylbisboronic Esters

钯催化烷基双硼酸酯交叉偶联反应

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Abstract

A Pd-catalyzed cross-coupling between alkylbisboronic esters and aryl bromides is described. A variety of aryl bromides are found to be competent substrates in the reaction. Different alkyl chain lengths of the alkylbisboronic esters are examined, and a two-carbon linker is found to be of the optimal chain length. Several competition experiments are performed to better understand the mechanism of the reaction.

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