Study of Cytotoxic and Antibacterial Activity of Ag- and Mg-Dual-Doped ZnO Nanoparticles

银镁双掺杂氧化锌纳米粒子的细胞毒性和抗菌活性研究

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Abstract

A non-laborious process for the fabrication of silver and magnesium dual doped zinc oxide nanoparticles (Ag/Mg-ZnO NP) is described. The wurtzite ZnO nano-structures and the dual doped NP were analyzed by PXRD. SEM data showed the hexagonal morphology of our product, while the gathered anti-bacterial outcomes towards Streptococcus mutans bacteria through micro-dilution technic affirmed the enhanced performance of doped NP compared to the native ones. Furthermore, we gauged the toxic impacts of synthesized pure and Ag/Mg-ZnO NP against a breast cancer (MDA-MB-231) cell line through an MTT trial, which highlighted the superiority of the doped when compared to the native nanoparticles. In light of these comparisons, the applicability of Ag/Mg-ZnO NP in dental and medical science is proposed.

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