Abstract
BACKGROUND/PURPOSE: Behçet's disease (BD) is a chronic systemic vasculitis characterized by recurrent oral and genital ulcers, skin lesions, and uveitis. The purpose of this study was to analyze the scientometric characteristics and research trends of BD. MATERIALS AND METHODS: All the articles on BD were comprehensively retrieved from the Scopus database. Regional comparison (Turkey versus outside of Turkey) and chronological comparison (before 2010 versus after 2010) were performed. RESULTS: Among the 7023 articles on BD, Turkey was the country publishing most articles (2012 articles). In Turkey, questionnaire, quality of life, depression, and scoring system were distinctive keywords. In outside of Turkey, allele, gene expression, cytokine, interleukin 6, tumor necrosis factor-alpha, and phenotype were distinctive keywords. The trend of diagnostics mainly angiography before 2010 has changed to computed tomographic angiography, echocardiography, and optical coherence tomography. The trend of biology research has changed to research on metabolism, gene expression, allele, biomarkers, and genetic susceptibility after 2010. The trend of drug aspects mainly oral drug administration before 2010 has changed to drug withdrawal, drug dose reduction, drug safety, drug megadose, adalimumab, thalidomide, and salazosulfapyridine after 2010. CONCLUSION: This scientometric study elucidated the current scenario and research trends of BD, and would help in improving in reciprocal collaboration and communication for investigations on this disease.