Abstract
Diffuse esophageal intramural pseudo-diverticulosis (DEIPD) is a chronic fibrosing inflammation of the esophagus of unknown origin. Its name derives from the characteristic pseudo-diverticula formed by dilated ducts of submucosal glands. With an assumed prevalence of approximately 5-50/100 000, DEIPD is more frequent than previously estimated. It preferentially affects men between 50 and 70 years of age with a history of alcohol and tobacco abuse. Key symptoms are chronic dysphagia and food impactions. Typical endoscopic findings are multiple small, longitudinally aligned pseudo-diverticle openings and trachealization of the esophagus. Additionally, the usually gray mucosa may show a fine-grained pattern of very small red dots that merge into a pink tint, called "faux uni pattern." Once established, clinical symptoms and endoscopic changes persist throughout life. Although there is no known causal therapy, complications like bolus impactions, candida infections, or reflux can and should be treated.