Abstract
Invasive lobular carcinoma is the second-most-common subtype of breast cancer. It is characterized by a different metastatic pattern with a propensity to metastasize to pleura, peritoneum, gastrointestinal tract, and ovary. We report a woman with known metastatic disease outside the gastrointestinal tract who had endoscopy and colonoscopy for gastrointestinal symptoms. Extensive metastases were found in the stomach and colon with a diffuse infiltration of signet ring-like cells at histology and immunohistochemical findings consistent with breast carcinoma. To the best of our knowledge, this is the first report of such a case from Africa.