Analysis of Changes in Plasma Cytokine Levels in Response to IL12 Therapy in Three Clinical Trials
三项临床试验中 IL12 治疗后血浆细胞因子水平变化分析
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作者：Emily Schwarz, Brooke Benner, Lianbo Yu, Fode Tounkara, William E Carson 3rd
| 期刊： | Cancer Research Communications | 影响因子： | 2.000 |
| 时间： | 2024 | 起止号： | 2024 Jan 10;4(1):81-91. |
| doi： | 10.1158/2767-9764.CRC-23-0122 | 种属： | Human |
| 方法学： | MSD | 靶点： | TGF-β1 |
| 研究方向： | 细胞生物学 | 细胞类型： | 其它细胞 |
Significance
IL12 activates immune cells and is used to treat cancer. The profile of circulating cytokines was measured in an exploratory fashion in patients with cancer that received IL12 in combination with mAbs. This correlative pilot study could serve as the basis for additional studies of IL12 effects on the production of immune cytokines.
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