High-throughput Sequencing to Identify Bacteremia in Children with Cancer

利用高通量测序技术识别癌症患儿的菌血症

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Abstract

Current methods to diagnose bacteremia are limited. In this pilot study of children with cancer presenting with fever, we determined the concordance between a novel high-throughput sequencing platform called BacCapSeq and blood culture. High-throughput sequencing had modest concordance with blood culture. Discordant organisms included those with both unlikely or potential clinical relevance.

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