Abstract
INTRODUCTION: The aim of this study was to report the frequency and impact of endoscopic response and remission on the risk of subsequent pouchitis in patients with Crohn's disease-like pouch inflammation (CDLPI) on therapy. METHODS: This was a single-center retrospective study of patients older than 18 years with CDLPI on therapy. RESULTS: Among 110 included patients with CDLPI in clinical remission, endoscopic remission was not significantly associated with a reduced risk of subsequent pouchitis when compared with endoscopic response. DISCUSSION: Endoscopic response, not remission, is sufficient to reduce the risk of subsequent pouchitis in patients with CDLPI.