Crystal structure determination of rac-11'-(1-acetyl-1H-indazol-3-yl)-11',11a'-di-hydro-10'H,17'H-spiro-[indene-2,18'-[5a,16b]methano-tri-indeno[1,2-b:1',2'-d:2'',1''-g]oxocine]-1,3,10',12',17'(10a'H)-penta-one aceto-nitrile 1.5-solvate

rac-11'-(1-乙酰基-1H-吲唑-3-基)-11',11a'-二氢-10'H,17'H-螺-[茚-2,18'-[5a,16b]甲桥-三茚并[1,2-b:1',2'-d:2'',1''-g]氧杂环辛烷]-1,3,10',12',17'(10a'H)-戊酮乙腈 1,5-溶剂化物的晶体结构测定

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Abstract

The title compound, C(46)H(26)N(2)O(7)·1.5CH(3)CN, is the aldol condensation product of bindone with indazole-3-carbaldehyde followed by double inter-molecular cyclization. The asymmetric unit, which has monoclinic P2(1)/c symmetry, contains two independent mol-ecules of the title compound and three aceto-nitrile mol-ecules. The title mol-ecule comprises a central eight-membered ring, which contains an enol-ester, from which five arms extend. The arms exhibit inter-molecular inter-actions within the crystal lattice between mol-ecules of the title compound and with co-crystallized solvent mol-ecules (aceto-nitrile).

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