Abstract
OBJECTIVES: To determine the relationship of body mass index (BMI) with breath-holding time (BHT) as well as that of BHT with the duration of hyperventilation (DOH) in young healthy adults. METHODS: An observational study was performed at Shalamar Medical and Dental College, Lahore, Pakistan, between May 2021 and June 2022. Healthy first-year Bachelor of Medicine, Bachelor of Surgery students aged 18-22 years, with a normal BMI were included. Spirometric measurements were taken through a spirometer pod connected to a pneumotachometer (model: Power Lab 26T). Body mass index was calculated as the weight (kg) to height (m(2)) ratio. Pearson correlation, linear regression, and t tests were applied using SPSS. RESULTS: A total of 101 subjects participated, comprising of 44 men and 57 women. A weak negative association was found between BMI and BHT in all subjects (r= -0.08, p=0.34), in men (r= -0.24, p=0.11), and in women (r= -0.092, p=0.497). Furthermore, a strong association was observed between BHT and DOH in all subjects (r=0.64, p=0.000), in men (r=0.604, p=0.000), and in women (r=0.518, p=0.000). Moreover, a nonsignificant weak inverse linear regression was found between the BMI and BHT of all subjects (β= -0.087, p=0.38), of men (β= -0.241, p=0.11), and of women (β= -0.092, p=0.49). Lastly, a significantly strong positive regression was observed between the BHT and DOH of all subjects (β=0.637, p=0.000), of men (β=0.604, p=0.000), and of women (β=0.518, p=0.000). CONCLUSION: No association was found between BMI and BHT. A strong positive association was observed between BHT and DOH in all healthy young people.