Estimation of vitamin D deficiency prevalence among Saudi children in Armed Forces Hospital and Riyadh Care Hospital in Riyadh, Kingdom of Saudi Arabia and its relation to type 1 diabetes mellitus

对沙特阿拉伯王国利雅得武装部队医院和利雅得护理医院的沙特儿童维生素D缺乏症患病率进行估计,并探讨其与1型糖尿病的关系

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Abstract

To evaluate the prevalence of vitamin D deficiency among a group of Saudi children with type 1 diabetes mellitus (T1DM) in Armed Forces Hospital and Riyadh Care Hospital in Riyadh, Kingdom of Saudi Arabia. Methods: The study was carried out in Riyadh Armed Forces Hospital and Riyadh Care Hospital in Riyadh, Kingdom of Saudi Arabia, from January to June 2017. This study included a total of 100 Saudi (50 males and 50 females) participants with T1DM, aged 2-12 years old. Hemoglobin A1c (HbA1c) levels, serum calcium phosphorous and 25(OH) vitamin D were analyzed. Results: Seventy percent of the children with T1DM examined showed a reduced level of vitamin D. Vitamin D deficiency was more common in female children compared than male. Serum 25(OH) vitamin D was significantly inversely associated with body mass index as well as HbA1c. Conclusion: There is a concern that growing children with low vitamin D may be at higher risk for T1DM. It is necessary to further examine the mechanisms underlying vitamin D deficiency in T1DM children.

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