Lack of full sequencing GBA1 studies for patients with Parkinson's disease in Latin America

拉丁美洲缺乏针对帕金森病患者的GBA1基因全序列研究

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Abstract

Full sequencing of the GBA1 gene in patients with Parkinson's disease provides a wide screening of pathogenic variants, but less developed regions of the world, like Latin America, may have difficulties in performing full sequencing. We performed a systematic review with meta-analysis to explore the prevalence and the odds ratio of specific GBA1 variants in Parkinson's disease in Latin America. We noted a lack of full sequencing GBA1 studies in Latin America.

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