Activation and Functionalization of Organic Disulfides by Bis(Perfluoroalkyl) Complexes of Nickel(II)

镍(II)双(全氟烷基)配合物对有机二硫化物的活化和功能化

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Abstract

The [(MeCN)(2)Ni-(R(f))(2)] platform was used to study the oxidative addition of 8,8'-diquinolyl disulfide. The oxidative addition proceeds to afford [Ni-(R(f))(2)(SR)(2)] intermediates, which then eliminate R(aryl)-S-R(fluoroalkyl) products through consecutive carbon-sulfur bond-forming steps. The high-valent states of the nickel complexes are required to reductively eliminate the cross-coupled product, and it was shown through stoichiometric reactions that both the singly and doubly oxidized states can trigger the S-C(perfluoroalkyl) bond forming reductive eliminations. These results show that such metal-mediated coupling reactions are viable and worthy of consideration in new methods development.

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