Ruthenacarborane-Phenanthroline Derivatives as Potential Metallodrugs

钌碳硼烷-菲咯啉衍生物作为潜在的金属药物

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Abstract

Ruthenium-based complexes have received much interest as potential metallodrugs. In this work, four Ru(II) complexes bearing a dicarbollide moiety, a carbonyl ligand, and a phenanthroline-based ligand were synthesized and characterized, including single crystal diffraction analysis of compounds 2, 4, and 5 and an observed side product SP1. Complexes 2-5 are air and moisture stable under ambient conditions. They show excellent solubility in organic solvents, but low solubility in water.

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